An extract augmented by fermentation
In Finland, Labio identified a fungus, Albatrellus confluens
that is rich in Grifoline, a molecule with a known impact on the modulation of TRPV-1. Drawing on their expertise in fermentation, they successfully activated the fungus’ metabolic levers to considerably increase the number of polyphenols and amount of Grifoline.
Anti-inflammatory, thermo-regulatory action
Coolin has been evaluated in relation to the harmful effects of inflammation: protecting from free radicals, modulating the inflammatory cascade (IL6 and Cox 2), regulating TRPV1, inhibiting the influx of Ca2+ ions and reducing MMP-1.
But, Labio also evaluated its thermo-regulatory properties in-vitro. Used at 5%, it reduced the temperature of the skin by 2.6° on average, from the first application.
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